Serre’s criterion of affineness characterizes affine morphisms of schemes in terms of exactness properties of the corresponding functors among the categories of quasicoherent sheaves.
If is a quasicompact morphism of algebraic schemes and is separated, then is affine iff it is cohomologically affine, that is, the direct image functor is exact.
EGA II 5.2.2, EGA IV 1.7.17
Akhil Mathew, Serre’s criterion for affineness as Morita theory, a blog post
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