Martin Bauer, Matthias Neubert, One Leptoquark to Rule Them All: A Minimal Explanation for $R_{D^{(\ast)}}$, $R_K$ and $(g-2)_\mu$, Phys. Rev. Lett. 116, 141802 (2016) (arXiv:1511.01900)

With the recent result $[$of LHCb$]$, for the first time a single observable affected by negligible theoretical uncertainties exhibits a deviation from the SM exceeding the $3 \sigma$ level. Equally striking is the overall coherence of the picture that emerges, especially in $b \to s \ell^+ \ell^-$ −transitions. As we shall show in this paper, combining all the $b \to s \ell^+ \ell^-$−observables in a very conservative way, the significance of the New Physics (NP) hypothesis formulated in 2014–2015 of a purely left-handed LFU-violating contact interaction has now reached a significance of $4.6 \sigma$.

$[\ldots]$ A more structural way of addressing the flavor structure of the model is the idea of implementing Pati-Salam unification